Gary Lawrence

Dr. Gary Lawrence is an Assistant Professor of Molecular Neurobiology in the School of Biotechnology at Dublin City University (DCU). His research focuses on functional neurobiology, particularly the role of neurotoxins like botulinum in understanding nervous system function and therapeutic applications for peripheral neuropathies. He holds a doctorate from Imperial College London, where he studied SNARE proteins in neurotransmitter release. Lawrence joined DCU in 2003 as a Research Lecturer and transitioned to his current role in 2023. His work investigates botulinum toxin effects on peripheral nerve types (motor, sympathetic, parasympathetic, sensory) and processes like synaptic transmission, neuropeptide exocytosis, and TRP channel signaling in pain pathways.

Education: PhD in Molecular Neurobiology from Imperial College London, followed by postdoctoral research there. Professional trajectory includes foundational roles in DCU’s International Centre for Neurotherapeutics established by Prof. Oliver Dolly.

Research interests emphasize botulinum toxin mechanisms, TRP channels in pain signaling, and membrane trafficking. Recent studies explore how TRP channels encode pain intensity and are modulated by neurotrophins. His lab uses primary neuron cultures, in vivo models, and toxin-based tools to dissect neuron-specific exocytosis pathways and SNARE protein roles.

Publications highlight advancements in toxin-based therapeutics, neuron type-specific effects, and pain signaling mechanisms. Collaborative efforts focus on translating neurotoxin research into clinical applications for neuropathic pain and autonomic disorders.

Lab/Team: Part of the International Centre for Neurotherapeutics at DCU, specializing in neurotoxin research and neuropharmacology.