Günter Mayer

Prof. Günter Mayer is a Professor at the University of Bonn's Life and Medical Sciences Institute (LIMES) and affiliated with the Faculty of Mathematics and Natural Sciences. His research focuses on aptamer technology, optogenetics, and targeted therapies, aiming to develop molecular tools for precise biological investigation and clinical applications. Key projects include using in vitro selection to engineer nucleic acids for diagnostics/therapeutics and exploring nucleic acid evolution principles to generate novel compounds.

His research addresses how aptamers can elucidate biological phenomena, design light-controllable RNA molecules, and create tools for high-precision diagnostics. Notable achievements include developing click-SELEX methods for aptamer selection, optoribogenetic systems for gene regulation, and RNA-based biosensors for metabolic monitoring.

Publications emphasize interdisciplinary approaches combining biochemical, molecular, and biophysical techniques. Work spans SARS-CoV-2 aptamer antivirals, immune modulation via T-cell activation, and anti-inflammatory aptamers for hypersensitivity treatment. Collaborations with groups like the NeurotechEU alliance highlight transdisciplinary impact.

Research infrastructure includes the Mayer Lab (website: http://www.mayerlab.de/), focusing on translating fundamental nucleic acid science into clinical solutions. Current efforts prioritize precision medicine applications and next-gen diagnostic platforms through systems biology approaches.