معرفی
Fumito Ito, MD, PhD is an Associate Professor of Surgery and Molecular Microbiology and Immunology, with a focus on translational cancer immunology. He serves as Co-Leader of the Translational and Clinical Sciences Research (TACS) Program, driving investigations into immune cell dynamics and tumor interactions.
Research Interests
His work centers on:
- Immune checkpoint inhibitors and combination therapies in melanoma
- CX3CR1+ CD8 T-cell biology across cancers
- Dendritic cell engineering and neoantigen vaccination
- Tumor microenvironment modulation in resistant cancers
- Role of inflammasomes in immunotherapy-induced toxicity
Publications Overview
Recent publications highlight his expertise in melanoma immunology, gut microbiome dynamics, and dendritic cell-based therapies. Key trends include:
- Multi-omic profiling of brain metastases
- Notch signaling in stem cell-derived dendritic cell generation
- Mechanisms of T-cell exhaustion and persistence
- Preclinical validation of localized immunomodulatory strategies
Labs and Teams
He contributes to the TACS Program, bridging clinical and translational research to advance cancer immunotherapy protocols and biomarker discovery.
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