Francesca Ieva

Francesca Ieva serves as Associate Head of the Health Data Science Centre at Human Technopole and Associate Professor of Statistics at the Politecnico di Milano, where she leads the MOX - Modeling and Scientific Computing laboratory within the Department of Mathematics. She also co-leads the Di Angelantonio & Ieva Group, a collaborative research team focused on integrating molecular data with clinical information to advance precision medicine.

Dr. Ieva received her PhD in Mathematical Models and Methods for Engineering in 2012. Her academic journey has positioned her at the forefront of health data science, bridging statistical methodology with biomedical applications.

Her research focuses on statistical learning in biomedical sciences, with particular emphasis on developing advanced models for integrating complex clinical data to inform predictions in clinical decision-making. Francesca's work spans multiple domains including:

• Development of novel survival analysis techniques for healthcare applications
• Integration of DNA methylation data for cardiovascular risk prediction
• Application of machine learning to clinical pathway analysis in mental health
• Innovative approaches to polygenic risk scoring incorporating SNP interactions
• Development of radiomics models for cancer prognosis and treatment response

Analysis of Dr. Ieva's recent publications reveals a strong trend toward federated learning approaches in healthcare data analysis, reflecting growing concerns about data privacy while maintaining analytical power. Her work increasingly integrates multiple data types (genomic, epigenetic, imaging, and clinical records) to create more comprehensive patient profiles for precision medicine applications. A notable pattern is her focus on translating complex statistical models into clinically actionable tools that can directly inform patient care and healthcare policy decisions.

As Associate Head of the Health Data Science Centre at Human Technopole, Dr. Ieva oversees a research group comprising epidemiologists, statisticians, and data scientists working collaboratively to bridge the gap between genotype and phenotype. The Di Angelantonio & Ieva Group develops innovative studies that integrate biomolecular data with medical records, imaging, and portable medical device data. Her team utilizes both existing healthcare data and newly generated population-based studies, applying novel analytical methods that integrate clinical epidemiology with health research to improve data interpretation.

Dr. Ieva actively mentors several PhD students including Andrea Lampis, Katherine Marie Logan, Alessia Mapelli, Michela Carlotta Massi, and Andrea Mario Vergani. Her research has been supported by collaborations with major healthcare institutions and likely receives funding from research councils and health technology initiatives, though specific grant details are not provided in the available information.