Felix Nägele

Felix Nägele, MD, is a researcher at the Department of Neurology at the University Medical Center Hamburg-Eppendorf (UKE). He holds a medical doctorate and is actively engaged in neuroscience research with a focus on stroke, brain imaging, and the relationship between systemic health conditions and brain function.

His primary research interests include:

• Stroke pathophysiology and treatment
• Cerebral small vessel disease
• White matter microstructural alterations
• Neuroimaging techniques including diffusion MRI
• Relationship between vascular risk factors and cognitive function
• Brain changes in psychiatric disorders
• Neurological consequences of SARS-CoV-2 infection

Dr. Nägele's work primarily involves large-scale population studies like the Hamburg City Health Study, examining how cardiac biomarkers, kidney function, periodontal disease, and other systemic factors correlate with structural brain changes and cognitive impairment. His research utilizes advanced neuroimaging techniques to investigate subtle microstructural brain alterations across various conditions.

His publications demonstrate an interdisciplinary approach spanning neurology, cardiology, nephrology, psychiatry, and infectious disease research. Recent work has focused on the relationship between atrial fibrillation and brain structure, kidney function and cerebral small vessel disease, and the neurological impact of SARS-CoV-2 infection.

Dr. Nägele collaborates extensively with senior researchers at UKE, particularly with Goetz Thomalla and Bastian Cheng, and his work appears in high-impact journals including Neurology, Stroke, and Alzheimer's & Dementia.