Fang-Cheng Yeh

Fang-Cheng Yeh, MD, PhD is an Associate Professor in the Department of Neurological Surgery at the University of Pittsburgh School of Medicine, where he has served since 2016 as Director of the Fiber Tractography Lab. His work bridges neurosurgical practice with advanced computational neuroscience methodologies.

He earned his MD from National Taiwan University (2006) and PhD in Biomedical Engineering from Carnegie Mellon University (2014), establishing a foundation for his interdisciplinary research approach.

Dr. Yeh specializes in Diffusion MRI, Tractography, and Connectomics, with significant contributions to medical image analysis and pathology informatics. He developed DSI Studio—an open-source diffusion MRI analysis platform cited in over 2,000 publications—which enables sophisticated brain connectivity mapping through features like GPU acceleration and cloud processing. His methodological innovations include correlational tractography (linking white matter pathways to clinical variables) and differential tractography (tracking longitudinal neural changes), advancing research in glioma, concussion, and brain fingerprinting.

His scientific recognition includes:

• Chancellor’s Commercialization Fund Award, Pitt Ventures First Gear Program, University of Pittsburgh, 2019

While the text does not specify student advising details, his research program actively collaborates on multidisciplinary projects including the Chuck Noll Foundation-funded concussion studies and 2024 investigations of 1p/19q co-deletion effects in glioma patients using graph-theoretical network analysis.

The Fiber Tractography Lab maintains DSI Studio while pioneering clinical applications of connectomics, with media coverage spanning Pittsburgh Post-Gazette, Nature World News, and futurity.org for breakthroughs like individual brain connectivity fingerprinting and minimally invasive surgical planning.