معرفی
Fabio Fusi is an Associate Professor at the University of Siena's Department of Biotechnology, Chemistry and Pharmacy. His laboratory is located at II lotto, I floor, room C_01_135b, Via Aldo Moro 2, Siena, with multiple contact numbers (+39 0577 235203, +39 0577 235375, +39 0577 235377, +39 0577 235378) and email fabio.fusi@unisi.it. He holds office hours by appointment on Mondays from 11:00 to 13:00.
Dr. Fusi's research focuses on pharmacology of vascular systems, with emphasis on ion channel modulation (particularly CaV1.2 and KCa1.1 channels), vasorelaxant mechanisms, and drug discovery. His work leverages natural products (flavonoids, propolis, labdane diterpenes) and synthetic derivatives to develop novel therapeutics for cardiovascular diseases and cancer. Key themes include structure-activity relationships, electrophysiological characterization, and molecular modeling of bioactive compounds.
Recent publications (2022-2025) demonstrate consistent investigation into: 1) Flavonoid derivatives as modulators of vascular ion channels, 2) Natural product-based vasodilators from propolis, citrus, and olive oil, 3) Strategies to overcome cancer multidrug resistance, and 4) Mitochondrial dynamics in vascular tone regulation. His research employs electrophysiology, functional assays, and computational approaches to elucidate mechanisms of action.
Dr. Fusi leads an active research team with dedicated laboratory facilities, evidenced by multiple lab phone extensions. While specific students, awards, and grants aren't detailed in source materials, his publication record confirms ongoing doctoral/postdoctoral supervision in pharmacology and medicinal chemistry.
