Fabian Grünewald

Dr. Fabian Grünewald is an Independent PostDoc in Molecular Biomechanics at the Heidelberg Institute for Theoretical Studies (HITS). His research focuses on advancing coarse-grained molecular dynamics simulations, particularly using the Martini force field, to study complex biological systems. He specializes in lipid nanoparticle design, membrane protein dynamics, and the development of computational tools for multi-scale modeling.

Key areas of investigation include:

• Protein conformational changes under environmental stress
• Biophysical mechanisms of membrane organization
• Applications of hybrid lipid-polymer membranes in biosensing
• Algorithm development for large-scale cellular simulations

His work bridges computational chemistry and biomedical engineering, with recent contributions to:

• Optimizing nanoparticle drug delivery systems
• Understanding SARS-CoV-2 membrane architecture
• Developing pH-sensitive simulation protocols

Grünewald collaborates extensively with experimental groups to validate computational models of cellular processes, emphasizing translational applications in nanomedicine and systems biology.