معرفی
PD Dr. Evi Stegmann is an Adjunct Professor at Eberhard Karls Universität Tübingen, affiliated with the Faculty of Science and the Interfaculty Institute of Microbiology and Infection Medicine (IMIT), where she leads the Microbiology/Biotechnology research group. Her laboratory focuses on antibiotic discovery, microbial secondary metabolism, and bacterial self-resistance mechanisms, utilizing approaches like genome mining, metabolic engineering, and synthetic biology.
Her research spans:
- Elucidation of antibiotic biosynthetic pathways (e.g., glycopeptides, [S,S]-EDDS).
- Engineering of Amycolatopsis strains for optimized antibiotic production.
- Investigation of self-resistance mechanisms in actinomycetes.
- Activation of silent secondary metabolite clusters.
Her publications emphasize antibiotic biosynthesis, metabolic engineering, and bacterial resistance, with recurring themes in glycopeptide optimization, enzyme mechanisms, and strain engineering. She mentors PhD students (e.g., Simone Edenhart, Naybel Hernandez Perez) and oversees projects funded by initiatives like ERASysAPP and DZIF. Her lab collaborates with groups such as Prof. Heike Brötz Österhelt and Dr. Yvonne Mast.
