معرفی
Esther Stoeckli is a Professor at the University of Zurich leading the Stoeckli Lab, which focuses on axon guidance, neural development, and neurodevelopmental disorders. Her research integrates cell signaling, gene function, and live imaging techniques to study neural circuit formation in vertebrates.
- Key Research Areas
- Axon guidance mechanisms in spinal cord and cerebellar development
- Role of ciliopathy-related genes (e.g., CPLANE1, KIF7) in nervous system development
- Integrative signaling pathways (Wnt, Sonic Hedgehog, Slit/Robo)
- Development of microscopy tools (mesoSPIM, light-sheet imaging)
- Trends in Recent Publications
- Focus on ciliopathy genes and their impact on peripheral/central nervous system development (2025–2024)
- Advancements in open-source microscopy for cleared tissue analysis (2024)
- Investigations of cell adhesion molecules in Purkinje cell migration and commissural axon pathfinding (2021–2022)
- Historical work on RNAi-based gene silencing in chicken brain development (2012)
- PhD Students
- Reto Cola (Cerebellar development, ciliopathy genes)
- Alexandra Noble (Joubert Syndrome models)
- Gonzalo Saiz Castro (Neurodevelopmental disorder genes)
- Joy Wyss (Extracellular vesicles in circuit formation)
- Moris Camporesi (Boundary cap cell clusters)
- Collaborations & Tools
- Co-development of mesoSPIM and multi-immersion microscope objectives with interdisciplinary teams (2024)
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