معرفی
Dr. Esther Sammler is a Clinical Senior Lecturer in Neuroscience at the University of Dundee, where she serves as a Principal Investigator at the MRC Protein Phosphorylation and Ubiquitylation Unit (PPU). Her research focuses on Parkinson's Disease, particularly investigating Leucine-rich Repeat Kinase 2 (LRRK2) and its role in neurodegenerative processes, with 52 research outputs documented through 2025.
Dr. Sammler's research interests include:
- Parkinson's Disease mechanisms and pathology
- LRRK2 kinase signaling pathways
- Genetic mutations in neurodegenerative diseases
- Connections between inflammation and Parkinson's
- Biomarker discovery for Parkinson's disease
- Clinical trial development
Analysis of Dr. Sammler's recent publications (2023-2025) reveals a concentrated focus on LRRK2-related research, with particular attention to genetic variants, structural and functional characterization of mutations, and connections to inflammatory pathways. Her work bridges basic science and clinical applications in Parkinson's disease, with publications appearing in high-impact journals including NPJ Parkinson's Disease, Movement Disorders, EMBO Reports, and Cell Reports.
Award recognition:
- Stephen Fry Award for Public Engagement (2019)
Dr. Sammler maintains an active research program with multiple funded projects, including international collaborations with institutions in Belgium, Germany, and Malaysia. She is deeply committed to public engagement, organizing events that connect researchers directly with people living with Parkinson's disease and translating complex science for public understanding. Her laboratory work at the James Black Building investigates molecular mechanisms underlying Parkinson's Disease with the goal of identifying new therapeutic approaches.
