Esther Brusse

Dr. Esther Brusse is a Researcher at Erasmus MC in the Department of Neurology. She focuses on immunological and neurological aspects of infectious diseases, particularly SARS-CoV-2 and autoimmune conditions. Her work explores vaccine efficacy in immunocompromised patients, management of Pompe disease through enzyme replacement therapy, and T cell dynamics in multiple sclerosis.

Her research interests include viral breakthrough infections in immunosuppressed populations, post-vaccination immune responses, and clinical outcomes in neuromuscular disorders. She contributes to European consortia like the T2B! Immunity group and the European Pompe Consortium, co-authoring guidelines for Pompe disease treatment (triple-S criteria) and improving outcome measurement tools.

Recent publications (2024) address patient-reported outcomes post-vaccination in neuromuscular diseases, clinical responses to SARS-CoV-2 breakthrough infections under immunosuppressants, and T cell biomarkers predicting vaccine failure in anti-CD20-treated MS patients.