Eric C. Bolton

Eric C. Bolton is an Associate Professor in the Department of Molecular & Integrative Physiology at the University of Illinois, affiliated with the School of Molecular & Cellular Biology. His research focuses on understanding the molecular mechanisms of prostate development and neoplasia, particularly the role of androgen receptor (AR) signaling in hormone-dependent cancers and developmental pathways. He holds a PhD from Johns Hopkins University and postdoctoral training at UCSF.

Research interests include the AR's role in cell proliferation/differentiation, crosstalk with growth factor pathways, and the transition from normal prostate development to cancer. He employs mouse models and organ culture systems to study prostate gland morphogenesis and AR-mediated stress responses. Recent work also explores KCNQ2 mutations linked to epileptic encephalopathy, highlighting interdisciplinary research into neuroendocrine mechanisms.

Teaching includes courses on human disease mechanisms and cancer pathophysiology. Bolton's lab investigates novel therapeutic targets for prostate cancer, including non-competitive AR inhibitors and pathways regulating cellular stress responses.