معرفی
Elsbeth van Liere is a Researcher and Teacher at Utrecht University's Faculty of Veterinary Medicine, Department of Biomolecular Health Sciences, and affiliated with the Hubrecht Institute. Her work focuses on cell biology and cancer research, particularly the roles of E2F transcription factors in polyploidization, replication stress, and tumorigenesis. She has contributed to understanding how oncogenic RAS and FOXM1 variation influence DNA damage responses and tumor biology, and discovered CDC6 as a novel canine tumor biomarker in circulating extracellular vesicles.
- Utrecht University
- Faculty of Veterinary Medicine
- Biomolecular Health Sciences
- Hubrecht Institute
Her research explores molecular mechanisms in cancer and developmental biology, with a focus on E2F family dynamics, hepatocyte ploidy, and biomarker discovery for veterinary oncology. Key themes include cell cycle regulation, DNA damage responses, and therapeutic implications of transcriptional networks. She has published extensively on topics like E2F7's tumor-suppressive role and polyploidization in mammalian organs.
Recent publications highlight trends in molecular oncology, including replication stress tolerance mediated by FOXM1, E2F transcriptional feedback loops, and the role of extracellular vesicles in tumor diagnostics. Her work bridges human and veterinary oncology through comparative models and translational studies.
Elsbeth van Liere has no scientific awards documented here. She collaborates on peer-reviewed articles but no individual student advising or grant details are provided in the available texts.
She is affiliated with the Hubrecht Institute and Utrecht University's Biomolecular Health Sciences department, contributing to multidisciplinary teams in cancer and cell biology research.
