Elliott SoRelle

Elliott SoRelle, PhD, is an Assistant Professor in the Department of Microbiology and Immunology at the University of Michigan Medical School. His laboratory focuses on understanding Epstein-Barr Virus (EBV)-host interactions at high resolution, with a particular emphasis on epigenetic regulation, cellular reprogramming during lytic reactivation, and spatial landscapes of virus-associated diseases. Dr. SoRelle employs cutting-edge techniques such as single-cell RNA sequencing, spatial transcriptomics, and advanced microscopy to investigate EBV-driven pathologies like lymphomas and autoimmune diseases.

Dr. SoRelle holds a PhD from Stanford University School of Medicine (2018), a BS and BA from Rice University (2012), and completed postdoctoral training at Duke University School of Medicine (2024). His research bridges fundamental virology with translational goals, aiming to inform treatments for EBV-associated diseases.

Recent work includes defining EBV's role in reprogramming B cell fate via the EBNA3A/3C-EZH2 axis, dissecting lytic reactivation's impact on cancer stemness, and leveraging spatial biology to map tumor microenvironments. Collaborations with clinicians at U-M and beyond drive translational applications of these findings.