Ellen Zhong

Ellen Zhong is an Assistant Professor of Computer Science at Princeton University, leading the E.Z. Lab for Molecular Machine Learning. Her research bridges AI and structural biology, focusing on cryo-EM/cryo-ET data analysis for protein structure-dynamics characterization.

• Ph.D. in Computer Science from MIT (2022)
• Former DeepMind AlphaFold team member
• Ex-D. E. Shaw Research in drug discovery

Key research domains include 3D Reconstruction, Protein Dynamics, Cryo-EM Heterogeneity, and Interpretability in Biomedical AI. She develops open-source tools like cryoDRGN-AI and cryoDRGN for high-throughput structural biology applications.

Recent publications demonstrate AI-cryo-EM synergy (2025) and heterogeneous dataset benchmarking (NeurIPS 2024). Her work has received Princeton's Junior Faculty Award (2025) for excellence in research and teaching.

• Scientific Recognition:
  • Junior Faculty Award, Princeton (2025)
• Notable Collaborations:
  • AlphaFold3 development (Nature 2024)
  • CryoDRGN-AI (Nature Methods 2025)

Lab members include computational biologists and machine learning researchers working on generative modeling and biomedical imaging. Current projects span in situ proteomics, diffusion-based structural sampling, and multimodal biomedical data fusion.