Elizabeth A. Middleton

Elizabeth A. Middleton, MD, is an Assistant Professor in the Department of Internal Medicine at the University of Utah. She holds triple board certification from the American Board of Internal Medicine in Critical Care Medicine, Pulmonary Disease, and Internal Medicine. Her academic appointments reflect specialization in pulmonary/critical care medicine within the Division of Public Health.

Education:

• Fellowship in Pulmonary/Critical Care Medicine, University of Utah
• Chief Resident in Internal Medicine, University of Utah
• Residency in Internal Medicine, University of Utah
• MD from University of Utah School of Medicine
• BS in Behavioral and Health Sciences, University of Utah

Research Focus: Dr. Middleton investigates hematological responses in critical illnesses, with emphasis on platelet biology, immunothrombosis mechanisms in sepsis and COVID-19, megakaryocyte function, and neutrophil extracellular traps (NETs). Her work bridges pulmonary medicine and hematology, examining how coagulation abnormalities contribute to respiratory failure in infectious diseases.

Publication Trends: Her recent articles (2021-2024) demonstrate consistent focus on platelet dysfunction in sepsis and COVID-19, with innovations in understanding thromboinflammatory pathways. Research frequently examines transcriptomic regulation of platelets, extracellular vesicles, autophagy mechanisms, and clinical applications for anticoagulation therapies.

Awards & Advising: No awards or student advising relationships are documented in the provided text. Collaborative research is evident through multicenter clinical trials including the ACTIV-3b/TESICO and PassITON COVID-19 studies.