Eline Hooijman

Eline Hooijman is a Researcher at the Radiology & Nuclear Medicine department of Erasmus MC, specializing in radiopharmaceutical development. Her work focuses on optimizing radiochemistry techniques for therapeutic agents like ²²⁵Ac and ¹⁷⁷Lu, particularly for prostate cancer targeting via PSMA and DOTA-TATE complexes.

• Key research areas include Actinium-225 and Lutetium-177 applications, Prostate-Specific Membrane Antigen (PSMA) therapy, and High Performance Liquid Chromatography (HPLC) for quality control.
• She collaborates with multidisciplinary teams on clinical translation, emphasizing Good Manufacturing Practice (GMP) and safety evaluation in phase I trials.

Her recent publications highlight advancements in radioligand therapy, including comparative studies of ²²⁵Ac-DOTA-TATE and ²²⁵Ac-PSMA-I&T. She has contributed to methodologies for radio-TLC/HPLC analysis and clinical implementation challenges of ²²⁵Ac-labeled compounds.

The consistency in her work underscores the intersection of nuclear medicine, oncology, and analytical chemistry in developing targeted radionuclide therapies for metastatic castration-resistant prostate cancer (mCRPC).