معرفی
Efstratios Mylonas is an Assistant Professor in the Department of Chemistry at the University of Ioannina, Greece. He leads research in the Laboratory of Biochemistry, focusing on structural biology, protein folding, and rational protein design. His work integrates biochemical, biophysical, and computational approaches to understand and engineer biological macromolecules.
Education:
- No explicit educational background listed in the provided text.
Research Interests:
Dr. Mylonas's research centers on the structural and functional characterization of biological macromolecules. His lab investigates:
- The regulation of the Type III Secretion System (T3SS) in bacterial pathogens like Pseudomonas syringae and Erwinia amylovora, aiming to uncover the molecular interactions that activate this virulence machinery.
- The rational design of artificial proteins using AI-driven structural prediction and experimental validation, targeting applications in biotechnology and biomedicine.
- The mechanisms of protein folding and how sequence dictates three-dimensional structure, leveraging tools like small-angle X-ray scattering (SAXS).
Scientific Contributions:
His recent publications span RNA structure, bacterial virulence, protein engineering, nanomaterials, and neurodegeneration. A consistent theme is the use of solution scattering techniques to probe dynamic macromolecular assemblies in near-physiological conditions.
Laboratory & Affiliations:
Dr. Mylonas directs the Laboratory of Biochemistry at the University of Ioannina. He collaborates internationally with teams across Europe and Asia, contributing to structural biology consortia and training programs.
