معرفی
Edie Goldsmith is a Professor and Department Chair of Cell Biology & Anatomy at the University of South Carolina School of Medicine Columbia. She also serves as the Biomedical Science Graduate Director and Principal Investigator of SC INBRE. Her research focuses on the extracellular matrix (ECM), fibroblast-myofibroblast transitions, and the role of biomechanical environments in cardiovascular diseases and cancer. Goldsmith's work explores nanotechnology applications, such as gold nanorods, to modulate collagen production and fibrosis.
Education:
- Bachelor of Science in Biochemistry, College of Charleston (1990)
- Ph.D. in Chemistry, University of North Carolina at Chapel Hill (1996)
- Postdoctoral Fellowship in Biology & School of Medicine, University of South Carolina (1999)
Research Interests: Goldsmith’s laboratory investigates ECM dynamics, fibrosis mechanisms in heart disease, and diabetes-induced cardiac remodeling. Her studies emphasize biomechanical signaling, nanoparticle-cell interactions, and therapeutic strategies to regulate fibroblast activity. Recent work highlights the use of gold nanorods to target fibrotic pathways in cardiac and cancer contexts.
Grants & Teams: As SC INBRE Director, she oversees initiatives to enhance biomedical research training and infrastructure. Her lab collaborates with engineers and clinicians to develop biomaterial-based therapies for fibrosis. Ongoing projects include studying maternal cardiac function in pregnancy and postpartum through genetic deletion models.
