Eden Amir

Dr. Eden Amir is a Professor at the Department of Cell & Developmental Biology, Hebrew University of Jerusalem. His research focuses on epigenetic regulation in cancer, particularly DNA methylation and chromatin dynamics. He leads a lab studying epigenetic silencing of tumor suppressor genes and its implications for cancer therapy. Amir collaborates with Prof. Yuval Dor on cell proliferation markers and develops transgenic mouse models for cancer research. He teaches advanced cell biology and chromatin structure courses. His work bridges epigenetics, chromatin biology, and cancer mechanisms, with contributions to understanding genomic instability in tumors.

Key research areas include: epigenetic silencing mechanisms, cancer epigenetics, chromatin remodeling in malignant rhabdoid tumors, and direct reprogramming of epigenetic defects. His lab employs mouse models, high-throughput genomic techniques, and computational analysis. Major findings include the role of macroH2A in gene silencing and the impact of DNA hypomethylation on tumor development.

Amir’s contributions to the field are evident in over 50 peer-reviewed publications, including studies in Nature and Science. He is affiliated with the Institute of Life Sciences and collaborates internationally. His research also explores therapeutic strategies targeting aberrant epigenetic states in cancer cells.