Eddy Sotelo Perez

Professor Eddy Sotelo Perez is a faculty member at the Faculty of Pharmacy, University of Santiago de Compostela, leading the ComBioMed research group at the Research Center in Biological Chemistry and Molecular Materials (CIQUS). His work bridges Medicinal Chemistry and Chemical Biology, focusing on G protein-coupled receptors (GPCRs) and innovative multicomponent synthetic strategies.

• Ph.D. in Organic Chemistry, University of Santiago de Compostela (2000)

The group pioneers 3D-printed heterogeneous catalysts for eco-friendly drug synthesis and develops biased ligands targeting adenosine, dopamine, and cannabinoid receptors. Recent publications highlight their expertise in GPCR modulation for conditions like Parkinson’s disease, cancer, and neuropathic pain.

Key article trends include:

• GPCR ligand discovery (adenosine, CB2, dopamine)
• 3D-printed catalytic systems
• Multicomponent reaction (MCR) applications in heterocycle synthesis
• Anti-inflammatory and anticancer multitarget agents

Students supervised:

• Claudia Gioe-Gallo (Ph.D. 2023), discovered CB2 agonists with anti-inflammatory/anticancer effects
• Rubén Prieto-Díaz (Ph.D. 2023), studied A2B antagonists for cancer immunotherapy

Labs/teams:

• ComBioMed: Industrial collaboration platform for drug discovery
• CIQUS: Singular research center for chemical biology
• Collaboration with Galician Ceramic Institute for 3D-printed catalysts