Dmitri Davydov

Dmitri Davydov is a Research Professor in the Department of Chemistry at Washington State University. His research focuses on enzymology and biophysics, particularly cytochrome P450 mechanisms, protein conformational dynamics, and systems biochemistry of drug metabolism. He has over 40 years of experience in molecular enzymology and high-pressure bioscience.

Education:

• Research Fellow (Biophysics), 1991-1993, Institut de Biologie Physico-Chimique, Paris, France
• Ph.D. in Biochemistry, 1987, Russian State Medical University, Moscow
• M.S. in Biochemistry, 1978, Lomonosov Moscow State University

Research Interests:
Dr. Davydov investigates protein-protein interactions in cytochromes P450, functional integration in drug metabolism ensembles, and high-pressure adaptations of enzymes. His work integrates biochemical experiments with advanced techniques like mass spectrometry, proteomics, and structural biology.

Articles Trends:
Recent studies explore non-additive enzyme interactions in hepatic drug metabolism, alcohol-induced changes in cytochrome P450 abundance, and structural-functional relationships in plant and deep-sea enzymes. Key themes include systems-level enzyme network analysis and translational applications in pharmacology.

Advising & Grants:
No formal advisees listed; however, collaborative projects involve proteomics and structural biology. Research supported by grants focusing on drug metabolism and enzyme adaptation mechanisms.

Labs & Teams:
Works within WSU Chemistry's biochemistry group, collaborating on interdisciplinary projects involving enzyme dynamics and systems biology. Engages in international partnerships studying marine enzymes and plant P450 systems.