معرفی
Dimitrios Moskofidis is a Professor at Augusta University's Medical College of Georgia, with joint appointments in the Department of Medicine, Department of Biochemistry and Molecular Biology, and The Graduate School. He is a key member of the Georgia Cancer Center and leads the Chaperone Biology & Metabolism Research Group.
His research spans molecular chaperone biology, heat shock transcription factors, cancer metabolism, viral pathogenesis, and immune regulation. Using genetically engineered mouse models, his lab investigates how HSP70, HSP90, and HSF1 regulate protein homeostasis, metabolic reprogramming, and tumorigenesis in diseases such as liver cancer, leukemia, and neurodegeneration.
The recent publications highlight a strong focus on HSF1 signaling in cancer progression, metabolic dysregulation in aging, immune evasion mechanisms, and chaperone-based neuroprotection. The work consistently integrates genomic, proteomic, and metabolic approaches, with a translational emphasis on therapeutic targeting of stress response pathways.
He is actively funded by multiple NIH R01 grants (CA132640, CA062130, AI55774), reflecting sustained research impact. His lab includes postdoctoral fellows, assistant scientists, and academic collaborators, particularly with Dr. Nahid F. Mivechi.
- NIH R01 CA132640
- NIH R01 CA062130
- NIH R01 AI55774
His team includes researchers such as Xiongie Jin, Jungeng Pang, and Caixia Xi, contributing to a dynamic and collaborative research environment focused on molecular oncology and stress biology.
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