Denise L. Doolan

Introduction

Denise L. Doolan is a prominent researcher affiliated with James Cook University, specializing in malaria, immunology, and infectious diseases. Her work focuses on vaccine development, pathogen-host interactions, and molecular biology. She has contributed extensively to understanding Epstein-Barr virus (EBV) and its association with malignancies, as well as malaria parasite dynamics and immune responses.

Research Interests

Her research spans multiple disciplines, including:

• Malaria Research: Investigating parasite biology, vaccine targets, and immune responses in murine models and human studies.
• Immunology: Studying T-cell biology, immune dysfunction in infections, and antibody responses to pathogens like EBV.
• Vaccine Development: Designing novel biologics and evaluating antigen candidates for malaria and other infectious diseases.
• Oncology: Linking viral infections (e.g., EBV) to cancer development and screening strategies.

Recent Articles

Her recent work highlights advancements in:

• Optimizing environmental DNA (eDNA) methods for microbial analysis.
• Characterizing EBV antibody signatures in Hodgkin lymphoma across populations.
• Developing protocols for stable RNA extraction and immune response quantification.
• Evaluating global EBV-related cancer burdens and molecular diagnostics.

Labs and Collaborations

She collaborates with global teams, including the Collaborative Study Group, contributing to interdisciplinary projects on parasitology, virology, and immunology. Her studies often involve multi-omics approaches and clinical trials.