Delphine Colevret

Delphine Colevret is a Researcher at the Department of Genetics and Evolution, University of Geneva, Switzerland, specializing in molecular mechanisms of regeneration and aging using Hydra as a model organism. Her work focuses on autophagy pathways and stem cell dynamics within the Physical Principles of Regeneration research group.

Her research investigates how evolutionary-conserved molecular machinery maintains tissue homeostasis, with particular emphasis on the ULK1 kinase's role in autophagosome formation. She examines how disruptions in autophagy lead to aging phenotypes and impaired regenerative capacity, using Hydra vulgaris (non-aging) and H. oligactis (aging-prone) models to identify critical regulatory factors.

Analysis of her 2020 publication reveals consistent focus on kinase signaling in regenerative contexts, demonstrating how ULK1 inhibition disrupts contractility and size maintenance in Hydra. This work bridges fundamental cell biology with translational aging research, highlighting autophagy as a central mechanism in longevity.

She operates within the Department of Genetics and Evolution at Sciences III campus (Quai Ernest-Ansermet 30, Geneva), collaborating under the departmental leadership of Professor Ivan Rodriguez in facilities supporting advanced regenerative biology research.