David de Sancho Sánchez

David de Sancho Sánchez is a Ramón y Cajal Research Fellow at the University of the Basque Country (UPV/EHU) and the Donostia International Physics Center (DIPC) in Spain. His research employs computational methods to study protein dynamics, folding mechanisms, and biomolecular interactions, with a focus on quantitative comparisons between theory, simulation, and experimental data.

Education & Training:

• Biophysical Chemistry training at San Pablo CEU and Complutense Universities
• PhD under Antonio Rey at Complutense University
• Postdoctoral work with Victor Muñoz (Spanish Research Council) and Robert Best (University of Cambridge)

Research Focus:
David's work spans protein folding landscapes, metal-binding proteins, mechanical unfolding, and phase separation. Recent investigations include amyloid-beta aggregation, titin mechanics in cardiac disease, and computational drug design for cancer and neurodegeneration. His methodologies integrate molecular dynamics, Markov state models, and force spectroscopy simulations.

Scientific Awards:

• Ramón y Cajal Fellowship (UPV/EHU)
• Ikerbasque Research Fellowship (CIC nanoGUNE)

Affiliations:
He leads computational research at UPV/EHU's Theoretical Chemistry Unit and collaborates extensively with experimental groups at DIPC, focusing on protein engineering and disease mechanisms.