David M Harlan

David M. Harlan is a Professor of Medicine at UMass Chan Medical School and Chief of Diabetes at UMass Memorial Medical Center. He serves as Co-Director of the Diabetes Center of Excellence and holds multiple faculty appointments across the T.H. Chan School of Medicine in departments including Medicine, Pediatrics, and RNA Therapeutics Institute.

Education:

• BS in Physiology from University of Michigan
• MD from Duke University

Research Interests focus on:

• Islet transplantation and tolerance mechanisms
• Autoimmune diabetes (Type 1) pathogenesis
• Human beta cell biology and regeneration
• Diabetes care delivery systems
• Immunomodulation in transplantation
• Translational diabetes research

Recent Publications highlight expertise in diabetes immunology, islet transplantation, and gene editing technologies, with notable work on HSV-1's role in autoimmune diseases and prime editing efficiency in beta cells. His research spans clinical trials, animal models, and human islet biology.

Clinical Trials & Grants include NIH-funded studies on diabetes therapies and collaborations in islet transplantation protocols.