معرفی
David Crich is a Professor and Georgia Research Alliance Eminent Scholar in Drug Design at the University of Georgia’s College of Pharmacy, Department of Pharmaceutical and Biomedical Sciences. His research focuses on organic chemistry, drug design, and the synthesis of novel antibiotics targeting multidrug-resistant pathogens. Key interests include aminoglycoside antibiotics, glycosylation mechanisms, and carbohydrate-protein interactions.
Education: Holds a DèsSc degree in Pharmaceutical and Biomedical Sciences. Research highlights include groundbreaking work on apramycin derivatives, glycosidation selectivity, and structural studies of enzymes like hUGDH using cryo-EM. His group (CRICH GROUP) develops innovative methods for synthesizing complex molecules with medicinal applications.
Awards: James Flank Norris Award and Eminent Scholar designation. Research has produced over 200 publications, with recent work addressing antibiotic resistance, enzyme inhibition, and antiviral strategies against coronaviruses.
Advances include designing BCR-ABL1 kinase inhibitors for chronic myeloid leukemia and developing novel glycosylation protocols using transition metal catalysis. His lab bridges organic chemistry with biomedical applications, emphasizing translational research for clinical impact.
