معرفی
David Chalmers is an Associate Professor in Medicinal Chemistry at Monash University's Faculty of Pharmacy and Pharmaceutical Sciences, affiliated with the Monash Institute of Pharmaceutical Sciences. He specializes in computational drug design, focusing on molecular dynamics simulations, machine learning, and peptide chemistry to develop novel therapeutics targeting diseases like heart failure, Alzheimer’s, and HIV.
His research integrates computational modeling with experimental validation to address challenges in drug-receptor interactions and drug formulation stability. He leads multiple interdisciplinary projects funded by the National Health and Medical Research Council (NHMRC) and collaborates globally on drug discovery initiatives.
- Research Interests: Computational chemistry, drug design, peptide analogues, AI-driven drug discovery, lipid-based formulations.
- Key Projects: Alpha1-adrenoceptor drug development for heart failure/Alzheimer’s, HIV reverse transcriptase inhibitors, mRNA lipid nanoparticle stability.
- Recent Work: Over 110 publications (2022-2025), including studies on peptide antagonists, molecular dynamics of drug formulations, and AI-enhanced molecular property prediction.
His work contributes to UN Sustainable Development Goals related to good health and well-being, advancing precision medicine through innovative computational approaches.
