David Brooks

Professor David Brooks is a leading academic at Newcastle University, specializing in neurodegenerative diseases with a focus on Alzheimer’s and Parkinson’s disease. His work integrates advanced neuroimaging techniques like PET and MRI to study molecular, vascular, and synaptic changes in neurodegenerative disorders. He leads multidisciplinary research into biomarker development, disease progression mechanisms, and therapeutic interventions.

His research emphasizes the interplay between neuroinflammation, amyloid pathology, and cholinergic dysfunction. Key areas include early detection of Alzheimer’s via cerebral blood flow and amyloid imaging, and understanding Parkinson’s disease heterogeneity through noradrenergic and dopaminergic subtyping.

Brooks collaborates extensively with institutions worldwide, contributing to clinical trials like the Cinpanemab study and the ELAD trial investigating GLP-1 analogues for Alzheimer’s. His work also explores exercise’s neuroprotective effects and animal models (e.g., minipigs) for translational research.