Darja Smirnova

Darja Smirnova serves as an Acting Scientific Assistant and Ph.D. student at the Department of Anaesthesiology, Intensive Care and Clinical simulations, Riga Stradins University. Her academic work centers on advancing critical care practices through innovative monitoring and therapeutic interventions for septic shock patients.

Her research portfolio spans:

• Septic Shock Pathophysiology and Management
• Microcirculation Monitoring via Remote Photoplethysmography
• Hemoperfusion and Endotoxin Adsorption Therapies
• COVID-19 Critical Care Complications
• Extracorporeal Membrane Oxygenation Applications
• Non-invasive Diagnostic Technologies

Smirnova pioneers engineering-clinical integrations to optimize sepsis treatment protocols and microcirculatory assessment in intensive care settings.

Analysis of her 2023-2025 publications reveals a dominant focus on oXiris hemofilter applications for endotoxin removal, quantitative microcirculation analysis via photoplethysmography, and critical airway management using ECMO. Her work consistently bridges biomedical engineering with bedside critical care to address sepsis-induced organ dysfunction.

She leads the doctoral project 'Endotoxin and cytokine adsorption properties of the AN69-based polyethyleneimine membrane in septic shock patients' (2022-2026) and contributes to national initiatives including 'Life with COVID-19' (Latvian Council of Science) and EU Structural Funds projects for university modernization. Her collaborations with Pauls Stradins Clinical University Hospital focus on optimizing extracorporeal blood purification protocols under Professor O. Sabelnikovs' mentorship.