معرفی
Daphne Merkus is a Full Professor in the Department of Cardiology at Erasmus MC, Faculty of Medicine, where she conducts advanced research in cardiovascular physiology and pathophysiology. Her work bridges translational and clinical cardiology, with a strong emphasis on microvascular function and ischemic heart disease.
Her research interests span coronary microvascular dysfunction, ischemic heart disease, pulmonary hypertension, diabetes-related cardiac complications, and heart failure with preserved ejection fraction. She employs large animal models to investigate mechanisms of coronary circulation and test therapeutic interventions, contributing significantly to translational cardiovascular science.
The recent articles highlight a consistent focus on coronary physiology, cardiac metabolism, and mechanistic insights into heart disease. Her work integrates molecular signaling (e.g., potassium), pharmacological modulation (e.g., trametinib), and hemodynamic analysis (e.g., ventriculo-arterial coupling), demonstrating a multidisciplinary approach to understanding and treating complex cardiovascular conditions.
She has supervised at least 13 academic works and is actively involved in major collaborative research networks. Her contributions to the field are evident through her extensive publication record in top-tier journals.
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