معرفی
Daniel Panaccione is a Professor in the Department of Plant and Soil Sciences at West Virginia University. He holds administrative roles as Program Coordinator of Environmental, Soil and Water Sciences and Assistant Director of Graduate Programs. His research focuses on the biosynthesis and biological significance of ergot alkaloids, fungal toxins with agricultural and pharmaceutical implications.
Research Interests: Panaccione's work explores the molecular genetic mechanisms and chemical pathways underlying ergot alkaloid production. These toxins affect pasture grasses in agriculture and serve as foundational compounds for medications treating dementia, migraines, and other conditions. His team uses genetic manipulation and chemical analysis to elucidate gene functions, reconstruct pathways, and assess virulence factors in fungal strains.
Publications & Research Trends: His recent studies (2014–2017) highlight collaborations on ergot alkaloid pathway engineering, hydroxylation processes in Neosartorya fumigata, and heterologous expression in Aspergillus fumigatus. The research bridges molecular genetics, biochemistry, and biotechnology, aiming to modify fungal alkaloid content for agricultural safety and pharmaceutical innovation.
Contact: Office location: G109 South Agricultural Sciences. Phone: (304) 293-8819.
