Daniel Marchal

Daniel Marchal is a Guest Scientist at the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, working within the AG Erb research group. His research focuses on developing synthetic biological solutions for carbon fixation and CO2 reduction, leveraging enzyme engineering and metabolic pathway design.

His primary research interests include synthetic biology, biochemistry, and metabolic engineering with specific emphasis on CO2-reduction pathways, thiamine diphosphate/CoA-dependent enzyme systems, and machine learning applications in enzyme design. His work bridges fundamental biochemical mechanisms with practical biotechnological implementations for carbon capture.

Analysis of his 2019-2025 publications reveals a consistent trajectory toward enhancing carbon fixation through novel synthetic pathways. Key themes include ATP-driven CO2 reduction to formate, glycolyl-CoA carboxylase optimization, and the development of aerobic CO2-reduction modules. His research demonstrates interdisciplinary integration of microbiology, computational biology, and metabolic engineering to address carbon conversion challenges.

Dr. Marchal operates within the AG Erb research group at the Max Planck Institute for Terrestrial Microbiology, contributing to cutting-edge projects in synthetic carbon fixation. The group maintains advanced laboratory facilities for in vivo pathway validation and enzyme characterization, supporting his work on new-to-nature metabolic modules.