Craig Platt

Craig Platt, MD, PhD, serves as an Assistant Professor of Pediatrics at Harvard Medical School and holds clinical appointments at Boston Children's Hospital. He is an Attending Physician in the Division of Immunology and Director of Flow Cytometry, with additional roles in the Precision Medicine Service. His clinical expertise spans allergic conditions, immunodeficiencies, and complex immune dysregulation disorders.

• PhD, Yale School of Medicine (2010)
• MD, Yale School of Medicine (2010)
• Residency, Boston Children's Hospital (2013)
• Fellowship in Allergy/Immunology, Boston Children's Hospital (2016)

Dr. Platt's research focuses on immune dysregulation mechanisms, primary immunodeficiencies, and diagnostic applications of flow cytometry. His work integrates genetic analysis with clinical phenotyping to advance precision medicine for immunological disorders. Key interests include T/B lymphocyte profiling, newborn screening for immunodeficiencies, and biologic therapies for rare immune conditions. His laboratory develops novel immune phenotyping methods to characterize immune dysregulation in patients with genetic variants.

Analysis of his recent publications reveals a strong emphasis on flow cytometry-based diagnostics (38% of articles), genetic mechanisms of immunodeficiency (29%), and clinical management of immune dysregulation (22%). Recurring themes include T-cell subset abnormalities, gene-disease curation frameworks, and SARS-CoV-2 interactions with immunodeficiencies. His work frequently bridges basic immunology with clinical applications through the Precision Medicine Service.

As Director of Flow Cytometry, Dr. Platt leads a core facility supporting immunological diagnostics and research. His clinical service spans Boston Children's Hospital locations in Boston and Lexington, Massachusetts, where he manages complex cases including primary immunodeficiencies, severe allergies, and immune-mediated lung diseases. The Precision Medicine Service collaboration enables genomic analysis for difficult diagnostic cases, particularly those involving novel genetic variants.