Craig H. Bassing

Craig H. Bassing, Ph.D. is a Professor of Pathology and Laboratory Medicine at the Perelman School of Medicine, University of Pennsylvania, with a secondary affiliation at Children's Hospital of Philadelphia. His work focuses on molecular mechanisms in lymphocyte development and immune system regulation.

• Education: B.A. in Biology from Johns Hopkins University (1992), Ph.D. in Biology from Duke University (1997).

Research Interests: Dr. Bassing investigates antigen receptor gene assembly, DNA damage responses, and feedback inhibition mechanisms in T and B cell development. His studies explore how chromatin folding, RAG endonuclease activity, and protein kinases like ATM regulate immune diversity and genomic stability.

Publications: Recent work highlights roles for locus folding, Cyclin D3, and RAG1 domains in enforcing monogenic TCR expression and allelic exclusion. Collaborative studies address V(D)J recombination pathways and ubiquitin ligase functions in immune cell maturation.