Constance Guille

Constance Guille is a Professor in the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina (MUSC) College of Medicine. Her work focuses on maternal mental health, postpartum depression, substance use disorders, and health disparities in women's healthcare. She leads multiple studies aimed at improving screening, treatment, and care coordination for pregnant and postpartum individuals, particularly through telehealth innovations.

Dr. Guille’s research includes evaluating text message-based interventions for mental health and substance use disorder screening (e.g., the Listening to Women program), assessing risk factors for cannabis relapse in postpartum women, and reducing healthcare disparities through technology-driven solutions. Her studies are conducted across MUSC Health facilities, including Columbia, Florence, and Lancaster Medical Centers, emphasizing community engagement and culturally sensitive practices.

Her professional contributions span clinical trials addressing postpartum complications, cultural competency in healthcare delivery, and optimizing maternal care pathways. She collaborates with interdisciplinary teams and actively involves diverse populations in her research to ensure equitable outcomes.