Christof T. Grewer

Christof T. Grewer is a Professor and Department Chair in the Department of Chemistry at Binghamton University (State University of New York). He holds a PhD in Physical Chemistry from Johann Wolfgang Goethe-University (Germany) and has held academic positions including Assistant Professor at the University of Miami and Associate Professor at Binghamton before becoming a full Professor. His research focuses on understanding membrane-bound transport proteins, particularly amino acid transporters, combining experimental and computational approaches to elucidate transport mechanisms and develop pharmacological inhibitors.

Education: PhD in Physical Chemistry, Johann Wolfgang Goethe-University, Germany (1993); Postdoctoral Fellow at Cornell University (1993-1996) and Max-Planck-Institute for Biophysics (1997-2003).

Research Interests: Biophysical chemistry, dynamics of transport processes, pharmacological tool development, computational modeling of transport mechanisms, and inhibitor synthesis. Current work targets secondary-active Na+-coupled transporters like glutamate and neutral amino acid transporters (ASCT2, SNATs), with applications in cancer therapy by blocking glutamine uptake.

Key Contributions: Published extensively on transporter mechanisms, including allosteric inhibition studies and computational design of ASCT2 inhibitors. Active in structural-functional analysis using electrophysiology, Poisson-Boltzmann modeling, and molecular dynamics.

Awards: No specific prizes mentioned in texts, though his work reflects significant academic recognition.