Christian Mertes

Christian Mertes is a researcher affiliated with the Chair of Computational Molecular Medicine at Technische Universität München (TUM). He holds a PhD (2021) and works as Chief Technical Officer at OmicsDiscoveries GmbH since 2024. Previously, he was a visitor at Stanford University (2020, 2017–2018) and a system administrator/research assistant at TUM. His education includes a B.Sc. (2011) and M.Sc. (2015) in Bioinformatics from TUM/LMU.

His research focuses on computational genomics, aberrant splicing detection, and multi-omics integration for Mendelian disease diagnostics. Key contributions include developing FRASER (for splicing analysis) and OUTRIDER (for gene expression outlier detection). His work bridges bioinformatics, clinical genetics, and algorithm development.

Publications highlight advancements in RNA-Seq analysis, proteogenomics, and diagnostic pipelines. He has collaborated with groups at Stanford, LMU Munich, and other institutions. Teaching involvement includes courses on data analysis in R and statistical methods for systems genetics.

Mertes’ lab (Chair of Computational Molecular Medicine at TUM) emphasizes translational bioinformatics, with projects addressing rare disease mechanisms and precision medicine applications. His work has implications for improving diagnostic rates in genetic disorders through integrated omics approaches.