Christian Gorzelanny

Christian Gorzelanny is a researcher affiliated with the Universitätsklinikum Hamburg-Eppendorf (UKE) and the Medical Faculty of the University of Hamburg. His work focuses on immunology, oncology, hematology, and vascular biology, with a particular emphasis on complement pathways, cancer metastasis, extracellular vesicles, and thrombosis. His research integrates molecular, cellular, and clinical perspectives to understand disease mechanisms in conditions like vasculitis, melanoma, and coagulation disorders.

Research Interests: His studies explore the interplay between the immune system, vascular biology, and tumor progression. Key areas include the role of complement activation in inflammation, the mechanisms governing metastasis formation, and the influence of extracellular vesicles on endothelial function. He investigates how proteins like thrombospondin-1 and heparan sulfate modulate disease processes, offering insights into potential therapeutic targets.

Recent Trends in Articles: Recent work highlights the regulatory functions of thrombospondin-1 in renal disease, the role of von Willebrand factor in cancer-associated thrombosis, and the impact of heparan sulfate on melanoma microenvironment dynamics. His findings bridge basic science and clinical applications, particularly in understanding how vascular and immune systems interact in pathological states.

Grants & Collaborations: While specific grants aren’t detailed here, his extensive publication record suggests sustained engagement with collaborative research networks. His work aligns with translational medicine goals, aiming to translate molecular insights into clinical outcomes.

Labs/Teams: Likely part of the UKE’s research centers, such as the Center for Cardiovascular Research or Experimental Medicine, given the focus on vascular and immunological mechanisms.