معرفی
Christian Capitini, MD, is a Professor and Division Chief at the University of Wisconsin–Madison, affiliated with the Department of Pediatrics, School of Medicine and Public Health, and the Stem Cell and Regenerative Medicine Center. He leads an NIH-supported laboratory focused on cell-based immunotherapies for pediatric cancers.
- Education: MD (specific institutions not detailed in text)
Research Interests:
Capitini's work centers on adoptive cellular therapies, including
- Natural killer (NK) cell and CAR T cell infusions for pediatric solid tumors (neuroblastoma, osteosarcoma, rhabdomyosarcoma)
- Engineering alternatively activated monocytes/macrophages using mesenchymal stromal cell exosomes to treat immune-related adverse events (GVHD, acute radiation syndrome)
- Non-viral CAR T cell generation and in vivo tracking methodologies
- Translational models bridging bone marrow transplant complications and cancer immunotherapy
Scientific Awards:
- Robert Connor Dawes Foundation Fellowship (2025)
Clinical Leadership:
He serves as a site Principal Investigator (PI) for multicenter trials, including GD2 CAR T cell therapy for neuroblastoma/osteosarcoma and Kymriah (CD19 CAR T) for high-risk B cell leukemia. Additionally, he sponsors a University of Wisconsin clinical trial expanding gamma delta T cells post-transplant.
Research Training:
Capitini mentors graduate students through programs like Cellular and Molecular Pathology (CMP), Cellular and Molecular Biology (CMB), and Comparative Biomedical Sciences (CBMS).
