Chi-Lien Cheng

Chi-Lien Cheng is a Professor in the Department of Biology at the University of Iowa, where she investigates fundamental mechanisms of plant development with emphasis on alternation of generations in land plants and vegetative phase change in maize. Her research program leverages the model fern Ceratopteris richardii to dissect asexual life cycle transitions and identify evolutionarily conserved genetic pathways.

Education:

• PhD, University of Connecticut

Dr. Cheng's research integrates genetics, molecular biology, and evolutionary perspectives to understand how plants regulate developmental transitions across generations. Her laboratory focuses on molecular mechanisms controlling gametophyte-sporophyte switching in ferns and phase change in maize, utilizing genomic, transcriptomic, and functional approaches to elucidate conserved regulatory networks. This work provides critical insights into the evolution of developmental processes from non-seed to seed plants.

Analysis of her 15 most recent publications (2018-2025) reveals three dominant research trajectories: (1) WOX gene family evolution and function in fern gametophyte development, (2) hormonal and epigenetic regulation of vegetative phase change in maize, and (3) molecular adaptation mechanisms in mangroves under environmental stress. Her publications consistently bridge model systems—from ferns to maize to mangroves—demonstrating how comparative approaches uncover universal principles in plant development.

Dr. Cheng leads an active research laboratory that pioneered transformation techniques for Ceratopteris gametophytes, enabling genetic dissection of asexual reproduction pathways. Her team's identification of key genes in apogamy and apospory provides foundational knowledge for understanding apomixis in crop plants, with potential applications for agricultural innovation through clonal seed production.