Chengjie Xiong

Chengjie Xiong is a Professor of Biostatistics, Mathematics, and Neurology at Washington University in St. Louis. He holds affiliations with the Institute for Informatics, Data Science and Biostatistics (I2DB), Institute for Public Health, and Center for Biostatistics and Data Science (CBDS). His research focuses on Alzheimer's disease biomarkers, clinical trial methodologies, and neurodegenerative disease progression analysis.

Key research areas include cerebrospinal fluid biomarker studies, amyloid protein imaging, and the development of multi-analyte diagnostic panels. Recent work emphasizes evaluating disease-modifying therapies and understanding orexin-A's role in cognitive performance. Over 24,739 citations highlight his impactful contributions to neurology and biostatistics.

Recent publications (2025) analyze lecanemab treatment efficacy, gantenerumab's long-term safety, and the clinical meaningfulness of slowing cognitive decline metrics. Collaborations span global institutions in clinical neurology and biostatistical modeling.