Charlotte Laurfelt Munch Rasmussen

Charlotte Laurfelt Munch Rasmussen is an Assistant Professor and Veterinarian at the Biomedical Laboratory, Faculty of Health Sciences, University of Southern Denmark. She holds a DVM and PhD and is actively engaged in neuroscience and biomedical research, with a focus on the blood-brain barrier, gene therapy for rare neurological diseases, and drug delivery mechanisms.

Research Interests:

• Neuroscience and neurodegenerative disorders
• Blood-brain barrier physiology and transport
• Gene therapy, particularly using adeno-associated viruses (AAV)
• Pharmacokinetics and bioavailability enhancement
• Rare diseases, especially Niemann-Pick type C
• Drug delivery systems and transporter modulation

Her recent publications highlight a strong focus on preclinical models of rare diseases, adherence to research standards (ARRIVE guidelines), and strategies to improve CNS-targeted therapies. She frequently investigates molecular changes at the blood-brain barrier in response to pharmacological agents.

Scientific Contributions:

• Co-authored key papers on gene therapy for Niemann-Pick type C2 disease
• Published on improving oral bioavailability of antibiotics via inhibition of CYP3A4 and P-gp
• Investigated valproic acid’s effect on blood-brain barrier transporters
• Advocated for transparent reporting in preclinical gene therapy studies

Dr. Rasmussen collaborates with researchers across neuroscience, pharmacology, and proteomics. While no formal advising or grant details are listed, her active publication record indicates ongoing research leadership. She contributes to open-access science and is cited in news and academic platforms like Mendeley and Bluesky.