Charles Yu Liu

Charles Yu Liu is a Clinical Professor at the University of Southern California (USC) with appointments in Neurosurgery, Psychiatry and the Behavioral Sciences, Surgery, and Biomedical Engineering via the Viterbi School of Engineering. He serves as Director of the USC Neurorestoration Center and Surgical Director of the USC Comprehensive Epilepsy Program, a global leader in surgical epilepsy treatment.

• Undergraduate: Chemical Engineering, University of Michigan, Ann Arbor
• PhD: Chemical/Biomedical Engineering, Rice University
• MD: Yale University School of Medicine

Liu specializes in neurorestoration, focusing on restoring function to injured nervous systems through advanced neurosurgical tools and brain-computer interfaces. His research integrates neuroscience, biomedical engineering, and clinical neurosurgery to address epilepsy, stroke recovery, and neuromodulation therapies.

His 15 most recent publications (2025-2024) span Biomedical Engineering, Neuroscience, and Neurology, with subfields including neural interfaces, beta-band oscillations, neuroprosthetics, and neuroimaging. Key themes involve decoding motor and cognitive neural signals, improving deep brain stimulation parameters, and exploring SARS-CoV-2 neurotropism.

Liu chairs the Department of Neurosurgery at Rancho Los Amigos National Rehabilitation Center and collaborates with institutions like Caltech. He serves as Associate Editor of World Neurosurgery and consults for the NCAA USC Trojans Athletics Department on neurosurgical safety.