معرفی
Chad Borges is an Associate Professor at Arizona State University (ASU) with joint appointments in the School of Molecular Sciences and the Biodesign Institute, specifically its Piper Center for Personalized Diagnostics. His work bridges analytical chemistry, biochemistry, and biospecimen science, with a focus on developing innovative techniques for glycan and protein posttranslational modification (PTM) analysis. He serves as a Health Solutions Ambassador for ASU’s College of Health Solutions.
Education:
- Ph.D. in Analytical Toxicology, University of Utah (2001)
- B.S. in Chemistry, Walla Walla College (1997)
Research Interests: Dr. Borges’ research centers on glycan node analysis for bottom-up glycomics, quantifying PTMs (e.g., oxidation, glycation) as disease or sample integrity markers, and designing time-temperature indicators for biospecimen preservation. His lab develops methods to detect artifactual molecular changes in clinical samples, such as S-cysteinylated albumin (ΔS-Cys-Albumin), which reveals thawed-state exposure. He also explores glycan alterations in extracellular vesicles and their role in cancer progression.
Article Trends: His recent publications emphasize glycan node analysis for cancer diagnostics (lung, bladder), biospecimen integrity assessment via PTMs, and novel analytical methods using mass spectrometry. Collaborative studies with Mayo Clinic and others highlight glycan features as prognostic tools and the impact of storage conditions on clinical research reliability.
Scientific Recognition: His 2019 tenure and promotion to Associate Professor at ASU underscore his contributions. Students in his lab have received awards such as the John Kacoyannakis Award (for analytical chemistry excellence) and the Royal Society of Chemistry Certificate of Excellence.
Teaching & Advising: Dr. Borges mentors students in analytical chemistry and biochemistry, with recent advisees earning PhDs and Master’s degrees. His courses include Analytical Chemistry (CHM 325) and Research Techniques (BCH 392).
Labs & Collaborations: The Borges Lab collaborates with the Mayo Clinic and operates at the Biodesign Institute. They are commercializing visual time-temperature indicators through CryoVeritas, Inc., an ASU spin-off.