Celine M. Vachon

Celine M. Vachon is a Professor of Epidemiology at Mayo Clinic, located in Rochester, Minnesota. She holds a Regis Professorship in Breast Cancer Research (2025) and serves as a Consultant in the Division of Epidemiology within the Department of Quantitative Health Sciences. Her work focuses on two key areas: the genetic epidemiology of mammographic density as a breast cancer risk factor, and the genetic underpinnings of multiple myeloma and its precursor conditions.

Education:

• PhD in Epidemiology, University of Minnesota (Twin Cities)
• MS in Statistics, University of Minnesota (Twin Cities)
• BS in Mathematics, Michigan Technological University

Research Interests:

• Genetic factors influencing mammographic density and its role in breast cancer risk stratification
• Mechanisms linking mammographic density to specific breast cancer subtypes (e.g., ER+, luminal vs. basal)
• Genetic predisposition to multiple myeloma and monoclonal gammopathy of undetermined significance (MGUS)
• Collaborative GWAS projects with institutions including Washington University and Harvard University
• Clinical trials evaluating aromatase inhibitors' effects on mammographic density

Grants & Collaborations:

• Mayo Clinic Breast Cancer SPORE (2005-2025)
• Multiple Myeloma SPORE (2015-2025)
• National Cancer Institute-funded projects on myeloma genetics and clinical progression

Labs & Teams: Active in Mayo Clinic's Comprehensive Cancer Center, Women's Health Research Center, and the Quantitative Health Sciences division. Leads the Mayo Mammography Health Study and collaborates with the B-Cell Lymphoproliferative Disorders team.