Caroline H. Shiboski

Dr. Caroline H. Shiboski is a Professor in the Department of Stomatology at the University of California San Francisco (UCSF) School of Dentistry. She cares for adult and pediatric patients with oral mucosal diseases and other oral disorders, including inflammatory conditions (lichen planus, pemphigus, pemphigoid), infectious diseases (such as candidiasis and herpes virus infections), certain oral pain conditions (such as burning mouth syndrome), and the oral complications of graft-versus-host disease following stem cell transplants. She is also involved with the initial diagnosis of oral cancer and precancerous conditions, working closely with the head and neck surgery team for timely referral and treatment.

Dr. Shiboski's educational background includes:

• Lycee Rabelais, Versailles Academy, France, BS, 1978, Biology, Math, Physics
• Universite R. Descartes, Paris V, France, DDS, 1984, General Dentistry
• University of California San Francisco, Certificate, 1991, Advanced General Dentistry
• University of California, Berkeley, MPH, 1992, Epidemiology
• University of California San Francisco, Certificate, 1993, Dental Public Health
• University of California San Francisco, Certificate, 1994, Dental Clinical Epidemiology
• University of California, Berkeley, PhD, 1997, Epidemiology
• University of California San Francisco, Certificate, 1998, Oral Medicine

Dr. Shiboski's research primarily focuses on the oral manifestations of immune system dysfunction, oral cancer, and Sjögren's syndrome. Her work spans clinical investigations into oral mucosal diseases, epidemiological studies of oral conditions, and translational research connecting oral manifestations with systemic diseases. She has made significant contributions to understanding the oral complications of autoimmune disorders and has pioneered research on telemedicine applications in oral medicine, particularly during the COVID-19 pandemic.

Analysis of Dr. Shiboski's recent publications (2021-2023) reveals a strong emphasis on Sjögren's syndrome research, with multiple studies examining genetic, epigenetic, and clinical aspects of this autoimmune disorder. Her work also demonstrates growing interest in telemedicine applications for oral disease management, reflecting adaptation to modern healthcare delivery challenges. Additionally, she continues to investigate oral cancer disparities and the intersection of oral health with systemic conditions.

Dr. Shiboski has received numerous scientific awards throughout her career:

• Received High Honor for doctoral thesis titled "La prevention bucco-dentaire au Danemark" (1984)
• "Michele Bardet-Viatte Award" for best publication on Dental Health Promotion (1987)
• Dentist Scientist Award, Department of Stomatology, UCSF (2001)
• K23 award, Department of Stomatology, UCSF (2001)
• Diplomate of the American Academy of Oral Medicine (2001)
• Dean's Creativity fund Award (2003)
• Academic Senate New Investigator Award (2004)
• Teacher of the Year Award, Department of Stomatology, UCSF

Dr. Shiboski has secured substantial research funding as Principal Investigator on multiple NIH grants, most notably serving as PI for the Sjögren's International Collaborative Clinical Alliance Next Generation Studies (SICCA-NextGen) from June 2020-May 2025 (NIH U01DE028891). Her extensive grant portfolio demonstrates consistent funding support for over 25 years, with projects spanning oral health outcomes in transplant recipients, HIV-positive women, and Sjögren's syndrome research. While specific students aren't listed in the provided information, her role as Teacher of the Year Award recipient and involvement in resident education through UCSF suggests active mentoring.

Dr. Shiboski leads the Sjögren's International Collaborative Clinical Alliance (SICCA) research team, which has established a robust international network for studying Sjögren's syndrome. Her work with this consortium has generated significant insights into the genetic, clinical, and molecular aspects of this complex autoimmune disorder. The team has developed comprehensive clinical assessment protocols and biorepositories that have become valuable resources for the international research community studying autoimmune exocrinopathy.