Caroline Dias

Caroline Dias, MD, PhD, is a faculty researcher in the Department of Pediatrics at the University of Colorado Anschutz Medical Campus School of Medicine. Her work focuses on human genetics and neurogenetic mechanisms of brain development and degeneration, with emphasis on genetically defined disorders like Fragile X syndrome and single-cell genomic approaches.

Educational Background:

• BA in Neurobiology and Behavior from Cornell University
• MD, PhD from Icahn School of Medicine at Mount Sinai
• Pediatrics residency at Boston Combined Residency Program
• Developmental and Behavioral Pediatrics Fellowship at Boston Children’s Hospital

The Dias Lab explores molecular perturbations in neurodevelopmental and neurodegenerative disorders using single-cell sequencing on post-mortem human brain tissue. Their research prioritizes cellular heterogeneity, developmental context, and accessible methodologies to accelerate scientific discovery.

Recent publications highlight autism risk mechanisms through mosaic copy number variations (2021) and syndromic neurodevelopmental disorders linked to TCF7L2 variants (2021). Collaborative efforts within and beyond the university drive transformative research, particularly in human genetics.

The lab welcomes applicants at all levels interested in neurogenetic research, reflecting Caroline’s clinical work in Developmental Pediatrics at Children’s Hospital Colorado and her commitment to integrating research into patient care.